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Genetic Techniques for Biological Research : A Case Study Approach

	Author(s):	Corinne A. Michels
	Collection:
	Publisher:	Wiley
	Year:	2002
	Language:	English
	Pages:	237 pages
	Size:	2.65 MB
	Extension:	DJVU

[tab] [content title="Description"]Molecular Genetic Analysis is an advanced textbook to teach the theory and practice of molecular genetic analysis to senior undergraduates and graduates studying genetics, molecular biology and cell biology. This book uses a case study approach, with the yeast Saccharomyces as the model genetic organism, to explain the theory and practice of molecular genetic analysis. It provides enough information so readers will be able to apply the approach to their own research project. [/content] [content title="Content"] [/content] [content title="About the author"]Dr. Michels' professional career is dedicated to genetics - its teaching and use as a research tool to study all areas of biology and medicine. She first became interested in genetics as a college student majoring in biology. The Nobel Prize had recently been awarded to James Watson, Francis Crick, and Maurice Wilkins (1962) for revealing the structure of DNA and proposing how this molecule, known since 1943 to be the hereditary material, could duplicate and encode information for the formation of a living organism. After taking a course in biochemical genetics and learning about the work of other Nobel laureates who studied genetics, like Thomas Hunt Morgan (1933) of white eyed fruit fly fame; George Beadle and Edward Tatum (1958), the originators of the “one gene – one enzyme” hypothesis; and Joshua Lederberg (1958), who mapped the E. coli chromosome, Dr. Michels was hooked. She decided to train to be a geneticist with the goal of understanding the molecular basis of heredity, embryological development, disease, and human evolution. But it was only after the completion of her college senior thesis, on what was to be the Nobel Prize winning work of François Jacob, André Lwoff, and Jacques Monod (1965) on the genetic control of enzyme synthesis and virus replication, that she focused specifically on the regulation of gene expression. Dr. Michels' interest in genetics and the genetic approach to problem solving has been sustained throughout her career. [/content] [/tab]

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